Choosing a template (printables like reports & posters, presentations or infographics)
Select canvas height & width
Add, move or delete blocks
Insert objects or text/text frames
Change color/opacity of objects or text
Filter a bright image by adding a dark grey block and changing the opacity
Select and move multiple images using shift (neither ctrl nor command will work)
Resize or rotate objects proportionally using shift
Layer/group images - can be tedious to modify a layered image you have to un-layer them all, modify, then relayer. Layer/group as a last step (e.g. layers)
Edge, center alignment, alignment tool
Copy and paste elements from one infographic to another
Publish/Share (from dashboard or in edit mode)
Embed infographic (e.g. blog post)
Exporting an infographic or presentation to slideshare or evernote
Download infographic as image (png/jpg) or PDF
Masking photos
Uploading gifs (e.g. adding a gif to piktochart).
Chart functionality